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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
17.88
Human Site:
S1795
Identified Species:
32.78
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1795
R
V
R
K
N
A
D
S
K
N
N
L
N
A
E
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1795
R
V
R
K
N
A
D
S
K
N
N
L
N
A
E
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
E1272
F
T
V
E
K
P
D
E
N
F
S
C
A
S
S
Dog
Lupus familis
XP_536285
2273
247246
K1242
S
D
N
K
D
S
K
K
Q
N
L
K
N
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
S1793
R
V
R
K
N
T
D
S
K
V
N
V
N
T
E
Rat
Rattus norvegicus
P70478
2842
310514
S1793
R
V
R
K
N
T
D
S
K
V
N
V
N
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1800
R
V
K
K
N
A
D
S
K
N
N
F
N
M
E
Chicken
Gallus gallus
XP_001233411
2232
244958
K1201
G
P
G
L
D
D
D
K
T
E
E
G
D
I
L
Frog
Xenopus laevis
P70039
2829
310863
N1793
F
K
E
R
L
K
K
N
T
E
L
K
L
N
P
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
Q1710
I
H
K
P
F
R
V
Q
K
M
P
D
Q
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
Q1386
A
M
T
V
R
K
S
Q
Q
Q
E
S
Y
S
S
Honey Bee
Apis mellifera
XP_624558
2760
306907
S1728
Q
N
Q
N
H
T
G
S
L
E
N
L
L
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
P2127
G
K
I
R
S
I
T
P
P
K
S
V
L
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
6.6
20
N.A.
73.3
73.3
N.A.
80
6.6
0
13.3
N.A.
0
26.6
N.A.
0
P-Site Similarity:
100
100
26.6
40
N.A.
80
80
N.A.
86.6
20
13.3
26.6
N.A.
20
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
24
0
0
0
0
0
0
8
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
16
8
54
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
8
8
0
0
0
8
0
24
16
0
0
0
47
% E
% Phe:
16
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
16
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
16
16
47
8
16
16
16
47
8
0
16
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
0
8
0
16
24
24
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
8
8
8
39
0
0
8
8
31
47
0
47
24
0
% N
% Pro:
0
8
0
8
0
8
0
8
8
0
8
0
0
8
16
% P
% Gln:
8
0
8
0
0
0
0
16
16
8
0
0
8
0
8
% Q
% Arg:
39
0
31
16
8
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
8
47
0
0
16
8
0
16
24
% S
% Thr:
0
8
8
0
0
24
8
0
16
0
0
0
0
16
0
% T
% Val:
0
39
8
8
0
0
8
0
0
16
0
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _